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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
37 Results for "
Polygonum tinctorium Ait.
" in MedChemExpress (MCE) Product Catalog:
Products (37)
37 Results for "Polygonum tinctorium Ait." in MCE Product Catalog:
44
44 Publications Verification
Synonyms: STA 5326; LAM-002A free base; AIT-101
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Apilimod (STA 5326) is a potent IL-12/IL-23 inhibitor, and strongly inhibits IL-12 with IC50s of 1 nM and 2 nM, in IFN-γ/SAC-stimulated human PBMCs and SAC-treated monkey PBMCs, respectively . Apilimod is a potent and highly selective PIKfyve inhibitor.
44
44 Publications Verification
Synonyms: STA 5326 mesylate; LAM-002A; AIT-101 mesylate
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Apilimod (STA 5326) mesylate is a potent IL-12/IL-23 inhibitor, and strongly inhibits IL-12 with IC50s of 1 nM and 2 nM, in IFN-γ/SAC-stimulated human PBMCs and SAC-treated monkey PBMCs, respectively . Apilimod is a potent and highly selective PIKfyve inhibitor.
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1
1 Cited Publications
Cat. No.: HY-N2394
CAS No.: 38840-23-2
Category:
Quinones Rheum palmatum L. Polygonaceae Anthraquinones Phenols Polyphenols Plants Disease Research Fields Inflammation/Immunology
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1 Cited Publications
Cat. No.: HY-N11003
CAS No.: 155179-22-9
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Category:
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Cat. No.: HY-N0120
CAS No.: 65914-17-2
Synonyms: (E/Z)-Piceid
Category:
Stilbenes Polygonaceae Reynoutria japonica Houtt. Phenols Polyphenols Plants Disease Research Fields Inflammation/Immunology
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Tembotrione is a herbicide belonging to the HPPD (dioxygenase) inhibitor class with crop selectivity. Tembotrione effectively controls a variety of weeds including broadleaf and gramineous species by disrupting carotenoid synthesis, which leads to chlorophyll degradation and leaf whitening. Mixing Tembotrione with isoxaflutole or adding surfactants optimizes its efficacy and reduces phytotoxicity, with no residual impact on subsequent cruciferous crops, thus helping to increase maize grain yield. The activity of Tembotrione decreases under drought conditions, and under specific conditions (such as double-dose treatment), it may cause reversible yellowing and even yield reduction in crops such as poppy .
Cat. No.: HY-N12348
CAS No.: 928262-58-2
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Cat. No.: HY-N1725
CAS No.: 122872-03-1
Category:
Natural Products Other Diseases Plants Compositae Disease Research Fields Erythrina arborescens Roxb.
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Cat. No.: HY-14644B
CAS No.: 870087-37-9
Synonyms: STA 5326 hydrochloride; LAM-002A free base hydrochloride; AIT-101 hydrochloride
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Apilimod (STA 5326) hydrochloride is a PIKFYVE kinase inhibitor that promotes NLRP3 inflammatory vesicle activation and IL-1β secretion. Apilimod hydrochloride has been shown to inhibit host cell proteases, which may prevent viral invasion but also block antiviral immune responses, potentially exacerbating immunosuppression in COVID-19.
Cat. No.: HY-N1141
CAS No.: 64032-49-1
Category:
other families Monophenols Ketones, Aldehydes, Acids Metabolic Disease Phenols Plants Disease Research Fields
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Cat. No.: HY-N16588
CAS No.: 1085706-32-6
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Synonyms: AIT-082
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Leteprinim potassium (AIT-082), a purine analog, is a neuroprotective agent and cognitive enhancer. Leteprinim potassium is a hypoxanthine derivative neurotrophic agent. Leteprinim potassium can induce brain-derived neurotrophic factor (BDNF) mRNA production following spinal cord lesions, and nerve growth factor (NGF) mRNA production in basal forebrain. Leteprinim potassium reduces glutamate toxicity in cultured hippocampal neurons. Leteprinim potassium increases heme-oxygenase 1 and 2 mRNA levels that play role in cellular defense against reactive oxygen species .
Cat. No.: HY-120251
CAS No.: 138117-50-7
Synonyms: AIT-082 free acid
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Research Areas:
Leteprinim (AIT-082 free acid), a purine analog, is a neuroprotective agent and cognitive enhancer. Leteprinim is a hypoxanthine derivative neurotrophic agent. Leteprinim can induce brain-derived neurotrophic factor (BDNF) mRNA production following spinal cord lesions, and nerve growth factor (NGF) mRNA production in basal forebrain. Leteprinim reduces glutamate toxicity in cultured hippocampal neurons. Leteprinim increases heme-oxygenase 1 and 2 mRNA levels that play role in cellular defense against reactive oxygen species .
Cat. No.: HY-134241
CAS No.: 38412-47-4
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Cat. No.: HY-N12575
CAS No.: 1345826-33-6
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Cat. No.: HY-N1665
CAS No.: 129724-43-2
Category:
Flavonoids Chalcones Polygonaceae Phenols Polyphenols Adiantum venustum Don Plants Disease Research Fields Cancer
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Cat. No.: HY-N3726
CAS No.: 350986-74-2
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
